Neuromodulation
Neuromodulation involves placing a soft electrode (wire) through the sacral opening near your tailbone that stimulates the nerves to the bladder. If successful, a pacemaker (similar to a cardiac pacemaker) is implanted that continuously provides an impulse to the electrode.
Botox (Onobotulinum toxin A) can be injected into the lining of the bladder and will paralyze the bladder muscle, possibly reducing pain and urgency. It wears off in 6-10 months, so the procedure would need to be repeated.